Portus Congress Center
8:00 – 8:45
Registration (at the registration desk)
8:45 – 9:00
Organizing Committee Chair's Opening Remarks – Djuro Josić
Session 1: Nucleic Acids
Chairs: Ziad El Rassi (Oklahoma State University, USA) and Djuro Josić (University of Pula, Croatia)
9:00 – 9:35
Enabling CIMmultus DEAE columns at scale for plasmid DNA capture
Justina Martinkienė, Astra Zeneca
9:35 – 10:00
High-quality, phase-appropriate plasmid manufacturing to accelerate advanced therapies
John Bowen, CBM
10:00 – 10:25
High throughput manufacturing of personalized plasmid DNA cancer vaccines
Kathrin Seyrl, Biomay
10:25 – 10:55
Coffee Break
Session 2
Chairs: Zoltán Kis (University of Sheffield, UK) and Rok Sekirnik (Sartorius BIA Separations, Slovenia)
10:55 – 11:20
Sartorius In-Line Lysis System: Pioneering Success in Plasmid DNA Isolation
Matevž Korenč, Sartorius BIA Separations
11:20 – 11:45
Debottlenecking vaccine manufacturing; effective supply of quality pDNA
Salomé de Sa Magalhaes, UCL
11:45 – 12:10
Biotechnological platform to obtain a minicircle DNA vaccine targeting cervical cancer
Ângela Sousa, CICS-UBI Online
12:10 – 1:10
Lunch (provided by the organizer)
Session 3
Chairs: Sara Sousa Rosa (UCL, UK) and Dan Peer (NeoVac, UK)
1:10 – 1:45
Optimization of scalable lentiviral plasmid production for GMP manufacturing
Robert Rodick, VxBiosciences
1:45 – 2:10
Novel, synthetic DNA templates for the production of mRNA
Carmen Mañas Torres, 4basebio
2:10 – 2:35
Purification of linearized template plasmid DNA decreases double-stranded RNA formation during IVT reaction
Diego Casabona Agudo, Certest Biotec
2:35 – 3:00
End-to-end solutions for IVT mRNA therapeutic development
Daniel Meng, VectorBuilder
3:00 – 3:30
Coffee Break
Session 4
Chairs: Salomé de Sa Magalhaes (UCL, UK) and Urh Černigoj (Sartorius BIA Separations, Slovenia)
3:30 – 3:55
Towards an efficient purification process for saRNA: exciting challenges and progress
Justine Jakpou, Ziphius Vaccines
3:55 – 4:20
The many struggles and success of the establishing a pDNA manufacturing platform
Ahmet Hilmi Tekin, BioNTech
4:20 – 4:45
mRNA vaccines: a perspective on process optimisation
Sara Sousa Rosa, UCL
4:45 – 5:00
YRC: Development of immobilized enzyme reactors on monolith backbone for rapid plasmid DNA linearization
Maša Strašek, Sartorius BIA Separations
5:00 – 5:15
YRC: Quality by design for mRNA platform purification based on continuous oligo-dT chromatography
Jixin Qu, University of Sheffield Online
5:30 – 7:00
Experts' Banquet (Congress Center) – networking, refreshments and snacks